Justin A Boddey Selected Research

plasmepsin (plasmepsin I)

1/2020	Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle.
6/2018	Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2 position of PEXEL peptidomimetics.
1/2018	Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte.
8/2015	Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes.
7/2014	Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.

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Justin A Boddey Research Topics

Disease

16	Malaria 12/2021 - 06/2009
8	Infections 12/2021 - 05/2010
1	Hepatocellular Carcinoma (Hepatoma) 05/2014

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 11/2021 - 06/2009
5	plasmepsin (plasmepsin I)IBA 01/2020 - 07/2014
4	Antimalarials (Antimalarial Agents)IBA 01/2020 - 05/2010
4	Aspartic Acid ProteasesIBA 10/2018 - 02/2010
2	VaccinesIBA 11/2021 - 05/2010
1	1- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA 12/2021
1	QuinazolinesIBA 12/2021
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2021
1	EpitopesIBA 11/2021
1	artemisinIBA 01/2020
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 10/2018
1	Phosphotransferases (Kinase)IBA 10/2018
1	ElementsIBA 06/2018
1	SubtilisinIBA 01/2018
1	FucosyltransferasesIBA 01/2017
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2017
1	PerforinIBA 01/2017
1	Pharmaceutical PreparationsIBA 08/2015
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 05/2014

Therapy/Procedure

1	Oral Administration 01/2020
1	Therapeutics 01/2020